by aporter@parthenonmgmt.com | Aug 22, 2025 | Clinical Pharmacology
There are several terms commonly used to describe adverse effects of drug therapy: An adverse drug reaction (ADR) is an unwanted or harmful reaction experienced following the administration of a drug or combination of drugs under normal conditions of use and is...
by aporter@parthenonmgmt.com | Aug 22, 2025 | Clinical Pharmacology
Prescribers choose treatment regimens on the basis that the benefits that accrue will outweigh the adverse effects. However, that outcome is never certain for individual patients even if the best evidence suggests that it is likely. The uncertainty arises for many of...
by aporter@parthenonmgmt.com | Aug 22, 2025 | Clinical Pharmacology
Patients make important contributions to rational prescribing decisions. Their beliefs and expectations affect the goals of therapy and help in judging the acceptable benefit/harm balance when selecting treatments. They will often play a key role in monitoring...
by aporter@parthenonmgmt.com | Aug 22, 2025 | Clinical Pharmacology
Prescribers have numerous sources of guidance about how to use drugs appropriately (e.g. dose, route, frequency, duration) for many conditions. However, this advice is based on average dose–response data derived from observations in many individuals. They can never be...
by aporter@parthenonmgmt.com | Aug 22, 2025 | Clinical Pharmacology
Clinical Pharmacology Clinical Pharmacology Introduction to clinical pharmacology Clinical pharmacodynamics Clinical pharmacokinetics Individual variation in drug response Adherence and concordance Therapeutic drug monitoring Adverse drug reactions Drug interactions...