by jmundell@parthenonmgmt.com | Oct 7, 2025 | Pharmacology
Immunopharmacology, as its name suggests, is the branch of pharmacology that applies to the immune system. In general immunopharmacology describes the manipulation of the immune system and immune responses by pharmacological modulators, for the benefit of the host....
by jmundell@parthenonmgmt.com | Oct 7, 2025 | Pharmacology
The sympathetic nervous (adrenergic) system: Drugs can modulate the activity of the sympathetic nervous system by affecting the synthesis, storage, release or reuptake of noradrenaline, or its interaction with adrenoceptors. A link to an animation showing the steps...
by jmundell@parthenonmgmt.com | Oct 7, 2025 | Pharmacology
The parasympathetic nervous system (PNS or cholinergic system): Acetylcholine is the major transmitter of the parasympathetic nervous system, but is also the transmitter at the ganglia of both the sympathetic and sympathetic nervous systems and the somatic nervous...
by jmundell@parthenonmgmt.com | Oct 7, 2025 | Pharmacology
Autonomic pharmacology is the study of how drugs interact with the autonomic nervous system. The autonomic nervous system plays an important role in the control of the internal organs including the heart, lungs, gastrointestinal tract and vasculature. Drugs which...
by jmundell@parthenonmgmt.com | Oct 7, 2025 | Pharmacology
Excretion is the removal of drugs and their metabolites from the body. Open All Other excretion Excretion with the bile (and thereby with feces), sweat, exhaled air, saliva, and breast milk play a much smaller role compared to urine. An exception is the excretion of...
by jmundell@parthenonmgmt.com | Oct 7, 2025 | Pharmacology
The primary objective of drug metabolism is to facilitate a drug’s excretion by increasing its water solubility (hydrophilicity). The involved chemical modifications incidentally decrease or increase a drug’s pharmacological activity and/or half-life, the most extreme...