by jmundell@parthenonmgmt.com | Oct 7, 2025 | Pharmacology
Drugs used in the clinic can have targets other than the major families of receptors, enzymes and ion channels. Pharmacologically important examples include but are not limited to transporters (both as drug targets and for their ability to modify drug action),...
by jmundell@parthenonmgmt.com | Oct 7, 2025 | Pharmacology
Enzymes are proteins which act as catalysts to facilitate the conversion of substrates into products. Enzyme classification has been developed by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB), which arranges...
by jmundell@parthenonmgmt.com | Oct 7, 2025 | Pharmacology
Ion channels are pore-forming protein complexes that facilitate the flow of ions across the hydrophobic core of cell membranes. They are present in the plasma membrane and membranes of intracellular organelles of all cells, performing essential physiological functions...
by jmundell@parthenonmgmt.com | Oct 7, 2025 | Pharmacology
Receptors are typically glycoproteins located in cell membranes that specifically recognize and bind to ligands. These are smaller molecules (including drugs) that are capable of ‘ligating’ themselves to the receptor protein. This binding initiates a...
by jmundell@parthenonmgmt.com | Oct 7, 2025 | Pharmacology
Pharmacodynamics is the study of how drugs have effects on the body. The most common mechanism is by the interaction of the drug with tissue receptors located either in cell membranes or in the intracellular fluid. The extent of receptor activation, and the subsequent...
by jmundell@parthenonmgmt.com | Apr 10, 2025 | Pharmacology
The study of how drugs act in living systems This section covers the basic principles of pharmacology including topics in pharmacodynamics and pharmacokinetics. It will introduce learners to some of the important generic principles of pharmacology that apply to the...
