by jmundell@parthenonmgmt.com | Oct 7, 2025 | Pharmacology
The parasympathetic nervous system (PNS or cholinergic system): Acetylcholine is the major transmitter of the parasympathetic nervous system, but is also the transmitter at the ganglia of both the sympathetic and sympathetic nervous systems and the somatic nervous...
by jmundell@parthenonmgmt.com | Oct 7, 2025 | Pharmacology
Autonomic pharmacology is the study of how drugs interact with the autonomic nervous system. The autonomic nervous system plays an important role in the control of the internal organs including the heart, lungs, gastrointestinal tract and vasculature. Drugs which...
by jmundell@parthenonmgmt.com | Oct 7, 2025 | Pharmacology
Excretion is the removal of drugs and their metabolites from the body. Open All Other excretion Excretion with the bile (and thereby with feces), sweat, exhaled air, saliva, and breast milk play a much smaller role compared to urine. An exception is the excretion of...
by jmundell@parthenonmgmt.com | Oct 7, 2025 | Pharmacology
The primary objective of drug metabolism is to facilitate a drug’s excretion by increasing its water solubility (hydrophilicity). The involved chemical modifications incidentally decrease or increase a drug’s pharmacological activity and/or half-life, the most extreme...
by jmundell@parthenonmgmt.com | Oct 7, 2025 | Pharmacology
Drug distribution is the process of delivering a drug from the bloodstream to the tissues of the body – especially the tissue(s) where its actions are needed. Open All Introduction to Drug Distribution The process of transferring a drug from the bloodstream to tissues...
